I use Splenda, occasionally, that is about it. Nutrasweet gives me the jitters. I try not to use any of them if I can avoid it.
I do use raw sugar, fruit juice or honey in recipes whenever I can get by with it and not really affect the taste. I know it doesn't help with the calories, but I feel like it is closer to the natural state of things, so it has to be healthier right? Probably it is just my illusion. When I use sugar I try to buy pure cane sugar.